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Hexapeptide-11

Names

[ CAS No. ]:
161258-30-6

[ Name ]:
Hexapeptide-11

[Synonym ]:
L-Proline,L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl
Hexapeptide-11

Biological Activity

[Description]:

Hexapeptide-11 is a bioactive peptide with anti-aging effect. Hexapeptide-11 protects fibroblasts against oxidative stress-mediated premature cellular senescence by mediating a downregulation of cellular proteins, such as ataxia telangiectasia mutated (ATM) and p53 [1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR
Research Areas >> Infection
Signaling Pathways >> Apoptosis >> MDM-2/p53
Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR

[References]

[1]. Errante F, et al. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. Front Chem. 2020;8:572923.  

Chemical & Physical Properties

[ Molecular Formula ]:
C36H48N6O7

[ Molecular Weight ]:
676.80200

[ Exact Mass ]:
676.35800

[ PSA ]:
201.71000

[ LogP ]:
4.09300

Related Compounds