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m-PEG5-CH2COOH

Names

[ CAS No. ]:
16142-03-3

[ Name ]:
m-PEG5-CH2COOH

[Synonym ]:
3,6,9,12,15,18-Hexaoxa-nonadecansaeure
3,6,9,12,15,18-hexaoxanonadecanoic acid
[2-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]acetic acid

Biological Activity

[Description]:

m-PEG5-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H26O8

[ Molecular Weight ]:
310.34100

[ Exact Mass ]:
310.16300

[ PSA ]:
92.68000

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds