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Azido-PEG8-Boc

Names

[ CAS No. ]:
1623791-99-0

[ Name ]:
Azido-PEG8-Boc

Biological Activity

[Description]:

Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

Alkyl/ether


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Garofalo, Antonio, et al. Efficient synthesis of small-sized phosphonated dendrons: potential organic coatings of iron oxide nanoparticles. New Journal of Chemistry (2014), 38(11), 5226-5239.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H45N3O10

[ Molecular Weight ]:
523.62

Related Compounds