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Huperzine C

Names

[ CAS No. ]:
163089-71-2

[ Name ]:
Huperzine C

Biological Activity

[Description]:

Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC50 of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s Disease[1][2].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

IC50: 0.6 μM (AChE)[2]


[References]

[1]. Fangfang Jiang, et al. Lycopodium alkaloids from Huperzia serrate. Fitoterapia.. 2019 Sep;137:104277.

[2]. Dong-Bo Zhang, et al. Lycodine-Type Alkaloids from Lycopodiastrum casuarinoides and Their Acetylcholinesterase Inhibitory Activity. Molecules. 2014 Jul; 19(7): 9999–10010.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H18N2O

[ Molecular Weight ]:
242.31600

[ Exact Mass ]:
242.14200

[ PSA ]:
59.14000

[ LogP ]:
2.96600

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds