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(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide

Names

[ CAS No. ]:
1632320-78-5

[ Name ]:
(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide

[Synonym ]:
Hydrazinecarbothioamide, 2-[[5-(4-nitrophenyl)-2-furanyl]methylene]-, (2E)-
5-(4-nitrophenyl)-2-furaldehyde thiosemicarbazone
(2E)-2-{[5-(4-Nitrophenyl)-2-furyl]methylene}hydrazinecarbothioamide
MFCD00695942

Biological Activity

[Description]:

F8-S43-S3 is an inhibitor of SARS-CoV-2 main protease, with an IC50 of 9.69 μM[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Dou X, et, al. Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main protease. Eur J Med Chem. 2022 Aug 5;238:114508.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H10N4O3S

Related Compounds