Bethoxazin

Names

[ Name ]:
Bethoxazin

[Synonym ]:
3-benzo[b]thien-2-yl-5,6-dihydro-1,4,2-oxathiazine 4-oxide
3-Benzo[b]thien-2-yl-5,6-dihydro-1,4,2-oxathiazine 4-oxide
Bethoxazin
1,4,2-Oxathiazine,3-benzobthien-2-yl-5,6-dihydro-,4-oxide
Bethoxazin [iso]
3-(1-benzothiophen-2-yl)-5,6-dihydro-1,4λ4,2-oxathiazin-4-one

Biological Activity

[Description]:

Bethoxazin(Bethoguard) is a new broad spectrum industrial microbicide with applications in material and coating preservation.IC50 value:Target: MicrobicideBethoxazin potently inhibited the catalytic activity of yeast DNA topoisomerase II and the growth of yeast BY4742 cells at low micromolar concentrations. bethoxazin may exert its microbicidal action by reacting with sensitive endogenous sulfhydryl biomolecules of microbial cells.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

Research Areas >> Others

[References]

[1]. Chee GL, et al. Chemical reactivity and microbicidal action of bethoxazin. Bioorg Med Chem. 2012 Feb 15;20(4):1494-501.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.581 g/cm3

[ Boiling Point ]:
452.334ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₉NO₂S₂

[ Molecular Weight ]:
251.32500

[ Exact Mass ]:
251.00700

[ PSA ]:
86.11000

[ LogP ]:
2.64310

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.779

[ Storage condition ]:
2-8℃

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318-H331-H373-H410

[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338-P311-P501

[ Hazard Codes ]:
T,N

[ Risk Phrases ]:
23-41-48/22-50/53

[ Safety Phrases ]:
26-36/39-45-57-60-61

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%