Burimamide oxalate
Names
[ CAS No. ]:
163932-06-7
[ Name ]:
Burimamide oxalate
[Synonym ]:
1-[4-(1H-Imidazol-4-yl)butyl]-3-methylthiourea ethanedioate (1:1)
Thiourea, N-[4-(1H-imidazol-5-yl)butyl]-N'-methyl-, ethanedioate (1:1)
Biological Activity
[Description]:
Burimamide oxalate is a potent dual H3/H2 receptor antagonist with Ki of 0.07 and 7.8 uM, respectively; shows weak affinity for H1, and has antinociceptive effects in vivo.
[References]
References 1. Wyllie JH, et al. Lancet. 1972 Nov 25;2(7787):1117-20. 2. Ambache N, et al. Br J Pharmacol. 1973 Jun;48(2):362P-363P. 3. Capurro N, et al. Br J Pharmacol. 1973 Aug;48(4):620-8. View Related Products by Target Histamine Receptor
Chemical & Physical Properties
[ Molecular Formula ]:
C11H18N4O4S
[ Molecular Weight ]:
302.350
[ Exact Mass ]:
302.104889