4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)propanamido)benzyl (4-nitrophenyl) carbonate
Names
[ CAS No. ]:
1639939-40-4
[ Name ]:
4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)propanamido)benzyl (4-nitrophenyl) carbonate
Biological Activity
[Description]:
MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[Related Catalog]:
[Target]
Cleavable
[In Vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C32H37N5O10
[ Molecular Weight ]:
651.66