MC-VC-PAB-Tubulysin M

Names

[ Name ]:
MC-VC-PAB-Tubulysin M

Biological Activity

[Description]:

MC-vc-PAB-Tubulysin M consists a cleavable ADC linker (MC-vc-PAB) and a cytotoxic tubulin inhibitor Tubulysin M (HY-N7053). Tubulysin M is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Auristatin

[References]

[1]. Wang Y, et al. Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules. Mol Pharmacol. 2016 Feb;89(2):233-42.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₆H₉₃N₁₁O₁₅S

[ Molecular Weight ]:
1312.57

Safety Information

[ Hazard Codes ]:
Xi

MC-VC-PAB-Tubulysin M

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds