Glycodeoxycholate Sodium

Names

[ Name ]:
Glycodeoxycholate Sodium

[Synonym ]:
2-[[(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid,sodium
3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide
Glycodesoxycholic acid
N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
EINECS 240-455-4
Sodium glycodeoxycholate
MFCD00036742

Biological Activity

[Description]:

Glycodeoxycholate Sodium is a bile salt.

[Related Catalog]:

Research Areas >> Metabolic Disease

Natural Products >> Steroids

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
0.9330g/cm3

[ Boiling Point ]:
655.6ºC at 760 mmHg

[ Melting Point ]:
207 °C

[ Molecular Formula ]:
C₂₆H₄₃NNaO₅

[ Molecular Weight ]:
472.61

[ Flash Point ]:
350.3ºC

[ PSA ]:
109.69000

[ LogP ]:
2.65030

[ Vapour Pressure ]:
5.74E-20mmHg at 25°C

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Precursor & DownStream

Precursor

DownStream

Articles

Functional role of oppA encoding an oligopeptide-binding protein from Lactobacillus salivarius Ren in bile tolerance.

J. Ind. Microbiol. Biotechnol. 42 , 1167-74, (2015)

Lactobacillus salivarius is a member of the indigenous microbiota of the human gastrointestinal tract (GIT), and some L. salivarius strains are considered as probiotics. Bile tolerance is a crucial pr...

Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans.

Drug Metab. Dispos. 43 , 851-63, (2015)

Inhibition of hepatic transporters such as organic anion transporting polypeptides (OATPs) 1B can cause drug-drug interactions (DDIs). Determining the impact of perpetrator drugs on the plasma exposur...

Mechanisms of cholesterol and saturated fatty acid lowering by Quillaja saponaria extract, studied by in vitro digestion model.

Food Funct. 6 , 1319-30, (2015)

Quillaja saponin extracts are known to reduce plasma cholesterol levels in humans. Here we study the mechanism of this effect with Quillaja Dry saponin extract (QD). In vitro model of triglyceride lip...