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DHODH-IN-2

Names

[ CAS No. ]:
1644156-80-8

[ Name ]:
DHODH-IN-2

Biological Activity

[Description]:

DHODH-IN-2 (compound 21d) is a human dihydroorotate dehydrogenase (HsDHODH) inhibitor, inhibits measles virus replication with a pMIC50 value of 8.6[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase

[Target]

IC50: HsDHODH[1]


[References]

[1]. Lucas-Hourani M, et al. Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).J Med Chem. 2015 Jul 23;58(14):5579-98.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H19BrN4O2

[ Molecular Weight ]:
403.27

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds