Trimetazidine-N-oxide

Names

[ Name ]:
Trimetazidine-N-oxide

Biological Activity

[Description]:

Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties.

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Inflammation/Immunology

[References]

[1]. Sigmund G, et al. Doping control analysis of trimetazidine and characterization of major metabolites using mass spectrometric approaches. Drug Test Anal. 2014 Nov-Dec;6(11-12):1197-205.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₂₂N₂O₄

[ Molecular Weight ]:
282.34

Trimetazidine-N-oxide

Names

Biological Activity

Chemical & Physical Properties

Related Compounds