6-Chloro-2-fluoropurine

Names

[ Name ]:
6-Chloro-2-fluoropurine

[Synonym ]:
6-Chloro-2-fluoro-1H-purine
6-Chloro-2-fluoropurine
T56 BM DN FN HNJ GF IG
7H-Purine, 6-chloro-2-fluoro-
6-Chloro-2-fluoro-9H-purine
6-chloro-2-fluoro-7H-purine
9H-Purine, 6-chloro-2-fluoro-
MFCD02183557

Biological Activity

[Description]:

6-Chloro-2-fluoro-9H-purine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Wilson, SC, Atrash, B., Barlow, C., et al. Design, synthesis and biological evaluation of 6 -pyridylmethylaminopurines as CDK inhibitorsBioorg. Med. Chem.19(22)6949-6965(2011)

[2]. Lee, K., Choi, Y., Gullen, E., et al.Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2',3'-unsaturated L-nucleotides J. Med. Chem.42(7)1320-1328(1999)

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
553.2±53.0 °C at 760 mmHg

[ Melting Point ]:
162-163°C

[ Molecular Formula ]:
C₅H₂ClFN₄

[ Molecular Weight ]:
172.55

[ Flash Point ]:
288.4±30.9 °C

[ Exact Mass ]:
171.995209

[ PSA ]:
54.46000

[ LogP ]:
0.07

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.698

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;Xn: Harmful;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%