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HIF-2α-IN-2

Names

[ CAS No. ]:
1672666-82-8

[ Name ]:
HIF-2α-IN-2

Biological Activity

[Description]:

HIF-2α-IN-2 is a hypoxia-inducible factors (HIF-2α) inhibitor extracted from patent WO2015035223A1, Compound 232, has an IC50 of 16 nM in scintillation proximity assay (SPA)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase

[Target]

IC50: 16 nM (HIF-2α)[1]


[References]

[1]. Darryl David DIXON, et al. Aryl ethers and uses thereof. WO2015035223A1.

Chemical & Physical Properties

[ Density]:
1.52±0.1 g/cm3(Predicted)

[ Boiling Point ]:
530.6±50.0 °C(Predicted)

[ Molecular Formula ]:
C17H13F2NO4S

[ Molecular Weight ]:
365.35

[ Storage condition ]:
2-8°C


Related Compounds