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PD1-PDL1 inhibitor 1

Names

[ CAS No. ]:
1675201-83-8

[ Name ]:
PD1-PDL1 inhibitor 1

[Synonym ]:
(2S)-1-{2,6-Dimethoxy-4-[(2-methyl-3-biphenylyl)methoxy]benzyl}-2-piperidinecarboxylic acid
2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)-
PD1-PDL1 inhibitor 1
PD-1/PD-L1 inhibitor 1

Biological Activity

[Description]:

BMS-1 is an inhibitor of the PD-1/PD-L1 protein/protein interaction.

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
Research Areas >> Inflammation/Immunology

[Target]

PD1-PDL1


[References]

[1]. Chupak Louis S,et al. Preparation of compounds useful as immunomodulators. From PCT Int. Appl. (2015), WO 2015034820 A1 20150312.


[Related Small Molecules]

PD-L1 inhibitor 1 | PD-1-IN-1 | Pembrolizumab | Avelumab | Sulfamethizole | BMS-1166 | PD1-IN-2

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
630.2±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C29H33NO5

[ Molecular Weight ]:
475.576

[ Flash Point ]:
334.9±31.5 °C

[ Exact Mass ]:
475.235870

[ LogP ]:
5.18

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.590

[ Storage condition ]:
-20℃

Related Compounds