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3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid

Names

[ CAS No. ]:
168293-14-9

[ Name ]:
3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid

[Synonym ]:
(3β,16α)-3-Acetoxy-16-hydroxylanosta-7,9(11),24-trien-21-oic acid
Lanosta-7,9(11),24-trien-21-oic acid, 3-(acetyloxy)-16-hydroxy-, (3β,16α)-

Biological Activity

[Description]:

3-O-Acetyl-16α-hydroxydehydrotrametenolic acid, an anti-inflammatory triterpenoid, inhibits NO production and iNOS expression in LPS-stimulated Raw264.7 cells[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase
Research Areas >> Inflammation/Immunology

[References]

[1]. Seoung Rak Lee, et al. Bioactivity-guided isolation of anti-inflammatory triterpenoids from the sclerotia of Poria cocos using LPS-stimulated Raw264.7 cells. Bioorg Chem. 2017 Feb;70:94-99.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
624.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C32H48O5

[ Molecular Weight ]:
512.721

[ Flash Point ]:
192.7±25.0 °C

[ Exact Mass ]:
512.350159

[ LogP ]:
7.81

[ Vapour Pressure ]:
0.0±4.1 mmHg at 25°C

[ Index of Refraction ]:
1.555

Related Compounds