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Epifriedelanol

Names

[ CAS No. ]:
16844-71-6

[ Name ]:
Epifriedelanol

[Synonym ]:
epi-Friedelanol
Friedelan-3α-ol
(3R,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a-octamethyldocosahydropicen-3-ol
(3R,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a-Octamethyldocosahydro-3-picenol
(3S,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a-Octamethyldocosahydropicen-3-ol
3Beta-Friedelanol
3-Picenol, docosahydro-4,4a,6b,8a,11,11,12b,14a-octamethyl-, (3R,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-
Epifriedelanol
3-Picenol, docosahydro-4,4a,6b,8a,11,11,12b,14a-octamethyl-, (3S,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-
3β-Friedelanol
3beta-Hydroxyfriedelane
(3S,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a-Octamethyldocosahydro-3-picenol
Epifriendelanol
epifriedelenol

Biological Activity

[Description]:

Epifriedelanol is a triterpenoid isolated from the root bark of Ulmus davidiana, with antitumor activity[1]. Epifriedelanol inhibits cellular senescence in human primary cells[2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Kundu JK, et al. Antitumor activity of epifriedelanol from Vitis trifolia. Fitoterapia. 2000 Sep;71(5):577-9.

[2]. Yang HH, et al. Epifriedelanol from the root bark of Ulmus davidiana inhibits cellular senescence in human primary cells. Planta Med. 2011 Mar;77(5):441-9.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
478.3±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H52O

[ Molecular Weight ]:
428.733

[ Flash Point ]:
199.6±12.3 °C

[ Exact Mass ]:
428.401825

[ PSA ]:
20.23000

[ LogP ]:
11.45

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.509

[ Storage condition ]:
2-8C

Related Compounds