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FTI-276 trifluoroacetate salt

Names

[ CAS No. ]:
170006-72-1

[ Name ]:
FTI-276 trifluoroacetate salt

[Synonym ]:
FTI 276

Biological Activity

[Description]:

FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase
Research Areas >> Cancer

[Target]

IC50: 0.9 and 0.5 nM for Plasmodium falciparum and human[1].


[References]

[1]. Chakrabarti D, et al. Protein farnesyltransferase and protein prenylation in Plasmodium falciparum.J Biol Chem. 2002 Nov 1; 277(44):42066-73. Epub 2002 Aug 22.


[Related Small Molecules]

Tipifarnib (R115777) | FTI-277 (hydrochloride) | L-778123 (hydrochloride) | Lonafarnib | BMS 214662 | LNK754 | Prenyl-IN-1 | RPR107393 free base | YM-53601 free base

Chemical & Physical Properties

[ Molecular Formula ]:
C21H27N3O3S2

[ Molecular Weight ]:
433.59

[ Appearance of Characters ]:
solid

[ Storage condition ]:
−20°C

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ WGK Germany ]:
3


Related Compounds