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1,4-Epidioxybisabola-2,10-dien-9-one

Names

[ CAS No. ]:
170380-69-5

[ Name ]:
1,4-Epidioxybisabola-2,10-dien-9-one

Biological Activity

[Description]:

1,4-Epidioxybisabola-2,10-dien-9-one is a 1,4-epidioxy-bisabola-2,12-diene derivate, which can be isolated from Curcuma longa L. 1,4-Epidioxybisabola-2,10-dien-9-one exhibits antiviral activity against influenza virus A/PR/8/34 (H1N1) in the MDCK cell line with an IC50 of 16.79 ± 4.03 μg/mL[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection

[In Vitro]

1,4-Epidioxybisabola-2,10-dien-9-one 对 MDCK 细胞具有细胞毒性，IC50 为 11.97 ± 5.72 μg/mL[1]。

[References]

[1]. Ti H , et al. Bisabolane-type sesquiterpenoids from Curcuma longa L. exert anti-influenza and anti-inflammatory activities through NF-κB/MAPK and RIG-1/STAT1/2 signaling pathways. Food Funct. 2021 Aug 2;12(15):6697-6711.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H22O3

[ Molecular Weight ]:
250.333

[ Storage condition ]:
2-8℃

Related Compounds