<Suppliers Price>

AZ PFKFB3 26

Names

[ CAS No. ]:
1704740-52-2

[ Name ]:
AZ PFKFB3 26

Biological Activity

[Description]:

AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

IC50: 23 nM (PFKFB3), 2.06 μM (PFKFB1), 0.384 μM (PFKFB2)[1]


[References]

[1]. Boyd S, et al. Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3. J Med Chem. 2015 Apr 23;58(8):3611-25.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H26N4O2

[ Molecular Weight ]:
402.49

[ Storage condition ]:
2-8℃

Related Compounds