terphenyl-d14

Names

[ CAS No. ]:
1718-51-0

[ Name ]:
terphenyl-d14

[Synonym ]:
(H)-1,1':4',1''-Terphenyl
deuterated 1,4-diphenylbenzene
tetradecadeuterio-p-terphenyl
perdeutero-1,4-diphenylbenzene
Deuterated p-Terphenyl
p-Terphenyl-d14
[2H14]Terphenyl
1,1':4',1''-Terphenyl-d
Perdeuterio-p-terphenyl
terphenyl-d14

Biological Activity

[Description]:

1,1':4',1''-Terphenyl-d14 is the deuterium labeled 1,1':4',1''-Terphenyl[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
400.0±12.0 °C at 760 mmHg

[ Melting Point ]:
212-213ºC(lit.)

[ Molecular Formula ]:
C18D14

[ Molecular Weight ]:
244.390

[ Flash Point ]:
188.1±13.7 °C

[ Exact Mass ]:
244.197418

[ LogP ]:
5.63

[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.602

[ Storage condition ]:
0-6°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Target Organs ]:
Blood, Central nervous system, Liver

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
3

Precursor & DownStream

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