Methyl oleanonate

Names

[ Name ]:
Methyl oleanonate

[Synonym ]:
3-Oxoolean-12-en-28-oic acid methyl ester
Methyl oleanonate

Biological Activity

[Description]:

Methyl oleanonate is a natural triterpene PPARγ agonist isolated from the species of Pistacia[1]. Methyl oleanonate is a modified oleanolic acid derivative with anti-cancer effects[2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

[Target]

PPARγ

[References]

[1]. Rasmus K Petersen, et al. Pharmacophore-driven identification of PPARγ agonists from natural sources. J Comput Aided Mol Des. 2011 Feb;25(2):107-16.

[2]. Barbara Bednarczyk-Cwynar, et al. Anticancer effect of A-ring or/and C-ring modified oleanolic acid derivatives on KB, MCF-7 and HeLa cell lines. Org Biomol Chem. 2012 Mar 21;10(11):2201-5

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₄₈O₃

[ Molecular Weight ]:
468.71100

[ Exact Mass ]:
468.36000

[ PSA ]:
43.37000

[ LogP ]:
7.53020

Methyl oleanonate

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds