2’-β-C-Methyl-6-azauridine

Names

[ Name ]:
2’-β-C-Methyl-6-azauridine

[Synonym ]:
1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2-C-methyl-β-D-ribofuranosyl)-
2-(2-C-Methyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione

Biological Activity

[Description]:

2’-β-C-Methyl-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Molecular Formula ]:
C₉H₁₃N₃O₆

[ Molecular Weight ]:
259.22

[ Exact Mass ]:
259.080444

[ LogP ]:
-1.57

[ Index of Refraction ]:
1.727