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(R)-(+)-goniothalamin

Names

[ CAS No. ]:
17303-67-2

[ Name ]:
(R)-(+)-goniothalamin

[Synonym ]:
(6R)-(+)-Goniothalamin
2H-Pyran-2-one, 5,6-dihydro-6-[(E)-2-phenylethenyl]-, (6R)-
Goniothalamine
(6R)-6-[(E)-2-Phenylvinyl]-5,6-dihydro-2H-pyran-2-one
(+)-(R)-goniothalamin
(R,E)-6-Styryl-5,6-dihydro-2H-pyran-2-one
Goniothalamin

Biological Activity

[Description]:

Goniothalamin (GTN) is styryllactone with anticancer, anti-inflammatory, immunosuppressive properties. Goniothalamin induces cytotoxicity, DNA damage and apoptosis of a variety of cancer cell lines[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Research Areas >> Inflammation/Immunology

[References]

[1]. Seyed MA, et al. Emerging anticancer potentials of goniothalamin and its molecular mechanisms. Biomed Res Int. 2014;2014:536508.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
386.0±41.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H12O2

[ Molecular Weight ]:
200.233

[ Flash Point ]:
162.3±25.0 °C

[ Exact Mass ]:
200.083725

[ PSA ]:
26.30000

[ LogP ]:
2.13

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.668

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds