<Suppliers Price>

PEG4-sulfonic acid

Names

[ CAS No. ]:
173459-90-0

[ Name ]:
PEG4-sulfonic acid

[Synonym ]:
Ethanesulfonic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-
2-{2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy}ethanesulfonic acid
MFCD29042364

Biological Activity

[Description]:

PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C8H18O7S

[ Molecular Weight ]:
258.289

[ Exact Mass ]:
258.077332

[ LogP ]:
-3.31

[ Index of Refraction ]:
1.486

Related Compounds