Tanshinone IIB

Names

[ Name ]:
Tanshinone IIB

[Synonym ]:
Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-6-(hydroxymethyl)-1,6-dimethyl-, (6S)-
(6S)-6-(Hydroxymethyl)-1,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione

Biological Activity

[Description]:

Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cardiovascular Disease

Research Areas >> Neurological Disease

[References]

[1]. Xue-Qing Yu, et al. Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro. Phytother Res. 2008 Jun;22(6):846-50.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
536.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₈O₄

[ Molecular Weight ]:
310.344

[ Flash Point ]:
278.5±30.1 °C

[ Exact Mass ]:
310.120514

[ PSA ]:
67.51000

[ LogP ]:
3.80

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.606

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%