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Sanggenol A

Names

[ CAS No. ]:
174423-30-4

[ Name ]:
Sanggenol A

[Synonym ]:
(2S)-2-{3-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl}-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-[3-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-, (2S)-

Biological Activity

[Description]:

Sanggenol A acts as a dual inhibitor of nitrofuranone reduction mediated by the intestinal microbial nitrification reductases EcNfsA and EcNfsB. In addition, Sanggenol A is also an effective inhibitor of intestinal bacterial β-glucuronidase[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Xi Chen, et al. Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases. Chem Biol Interact. 2022 Dec 1;368:110222.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
683.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H28O6

[ Molecular Weight ]:
424.486

[ Flash Point ]:
234.0±25.0 °C

[ Exact Mass ]:
424.188599

[ PSA ]:
107.22000

[ LogP ]:
6.60

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.629

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds