Tetramethylrhodamine-6-maleimide

Names

[ Name ]:
Tetramethylrhodamine-6-maleimide

[Synonym ]:
Tetramethylrhodamine-6-maleimide
MFCD01311092

Biological Activity

[Description]:

Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Geibel S, et al. Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):964-9.

[2]. Loo DD, et al. Conformational changes couple Na+ and glucose transport. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7789-94.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₂₃N₃O₅

[ Molecular Weight ]:
481.49900

[ Exact Mass ]:
481.16400

[ PSA ]:
97.13000

[ LogP ]:
3.52400

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S36

[ RIDADR ]:
NONH for all modes of transport