monolinuron
Names
[ CAS No. ]:
1746-81-2
[ Name ]:
monolinuron
[Synonym ]:
N’-(4-chlorophenyl)-N-methoxy-N-methylurea
3-(4-Chlorophenyl)-1-methoxy-1-methylurea
Monolinuron
MFCD00055264
EINECS 217-129-5
Urea, N'-(4-chlorophenyl)-N-methoxy-N-methyl-
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Melting Point ]:
76-78ºC
[ Molecular Formula ]:
C9H11ClN2O2
[ Molecular Weight ]:
214.649
[ Flash Point ]:
100 °C
[ Exact Mass ]:
214.050903
[ PSA ]:
41.57000
[ LogP ]:
2.30
[ Index of Refraction ]:
1.590
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS6425000
- CHEMICAL NAME :
- Urea, 3-(p-chlorophenyl)-1-methoxy-1-methyl-
- CAS REGISTRY NUMBER :
- 1746-81-2
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C9-H11-Cl-N2-O2
- MOLECULAR WEIGHT :
- 214.67
- WISWESSER LINE NOTATION :
- GR DMVN1&O1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969 Volume(issue)/page/year: 5,158,1976 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,261,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,261,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 4 gm/kg
- SEX/DURATION :
- female 10-13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,261,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 38,261,1977 *** REVIEWS *** TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973
Safety Information
[ Symbol ]:
GHS07, GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H373-H410
[ Precautionary Statements ]:
P273-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
22-60-61
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
YS6425000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Chromatogr. A. 1364 , 96-106, (2014)
Highly cross-linked monolithic networks (i.e., polyethylene glycol diacrylate, PEGDA) synthesized from monomers containing varying ethylene oxide chain lengths were fabricated inside fused silica capi...
Sonochemical and sonocatalytic degradation of monolinuron in waterUltrason. Sonochem. 18(5) , 1107-12, (2011)
Highlights ► Monolinuron is degraded by ultrasounds by OH or CO 3 - radicals. ► Ultrasound efficiency was improved in the presence of nanoparticles of TiO 2 and SiO 2 only at 20 kHz. ► Activated speci...
Investigation of photodegradation and hydrolysis of selected substituted urea and organophosphate pesticides in water.Environ. Sci. Pollut. Res. Int. 18(6) , 949-57, (2011)
Photodegradation and hydrolysis of two substituted urea herbicides, monolinuron [3-(4-chlorophenyl)-1-methoxy-1-methylurea] and linuron [3-(3,4-dichlorophenyl)-1-methoxy-1-methylurea], and one organop...