N-(4-Ethoxy-3-nitrophenyl)acetamide
Names
[ CAS No. ]:
1777-84-0
[ Name ]:
N-(4-Ethoxy-3-nitrophenyl)acetamide
[Synonym ]:
Essigsaeure-(4-aethoxy-3-nitro-anilid)
acetic acid-(4-ethoxy-3-nitro-anilide)
5-Nitro-p-acetophenetidide
Acetamide,N-(4-ethoxy-3-nitrophenyl)
3'-Nitro-p-acetophenetidin
4-ethoxy-3-nitroacetanilide
4-Acetamino-2-nitrophenetole
3-Nitro-p-acetophenetide
2-Nitro-4-acetamino-phenetol
p-Acetophenetidide,3'-nitro
Chemical & Physical Properties
[ Density]:
1.282g/cm3
[ Boiling Point ]:
429.6ºC at 760 mmHg
[ Melting Point ]:
123ºC
[ Molecular Formula ]:
C10H12N2O4
[ Molecular Weight ]:
224.21300
[ Flash Point ]:
213.6ºC
[ Exact Mass ]:
224.08000
[ PSA ]:
87.64000
[ LogP ]:
3.12460
[ Vapour Pressure ]:
1.38E-07mmHg at 25°C
[ Index of Refraction ]:
1.582
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AM4550000
- CHEMICAL NAME :
- p-Acetophenetidide, 3-nitro-
- CAS REGISTRY NUMBER :
- 1777-84-0
- BEILSTEIN REFERENCE NO. :
- 2735844
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C10-H12-N2-O4
- MOLECULAR WEIGHT :
- 224.24
- WISWESSER LINE NOTATION :
- WNR BO2 EMV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 957 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 478 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5(Suppl 1),3,1983
Safety Information
[ HS Code ]:
2924299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%