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3-(2-ETHYLPHENYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE

Names

[ CAS No. ]:
177951-34-7

[ Name ]:
3-(2-ETHYLPHENYL)-2-MERCAPTOQUINAZOLIN-4(3H)-ONE

[Synonym ]:
3-(2-ethylphenyl)-2-mercaptoquinazolin-4(3h)-one

Biological Activity

[Description]:

Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Jing Ma, et al. Combination of a thioxodihydroquinazolinone with cisplatineliminates ovarian cancer stem cell-like cells (CSC-LCs) andshows preclinical potential. Oncotarget. 2017 Dec 26;9(5):6042-6054.  

Chemical & Physical Properties

[ Molecular Formula ]:
C16H14N2OS

[ Molecular Weight ]:
282.36000

[ Exact Mass ]:
282.08300

[ PSA ]:
69.88000

[ LogP ]:
3.61070

Related Compounds