UNII:EU52DFC4WJ

Names

[ Name ]:
UNII:EU52DFC4WJ

[Synonym ]:
N-Methylaspartic acid
N-methyl-D,L-aspartate
N-methyl-D,L-aspartic acid
DL-Aspartic acid,N-methyl
DL-Aspartic acid, N-methyl-
N-Methyl-DL-Aspartic acid
DL-2-METHYLAMINOSUCCINIC ACID
Aspartic acid, N-methyl-
N-methylaminosuccinic acid
L-Aspartic acid,N-methyl
UNII:EU52DFC4WJ
N-Methyl aspartic acid
Aspartic acid,N-methyl

Biological Activity

[Description]:

N-Methyl-DL-aspartic acid is a glutamate analogue and acts as a potent neuronal excitant. N-Methyl-DL-aspartic acid is a NMDA receptor agonist and can be used for neurological diseases research[1][2].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[References]

[1]. G R Lauretti, et al. The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole. Neuropharmacology. 1994 Feb;33(2):155-60.

[2]. S J Czuczwar, et al. Antagonism of N-methyl-D,L-aspartic acid-induced convulsions by antiepileptic drugs and other agents. Eur J Pharmacol. 1985 Feb 5;108(3):273-80

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
258.2±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₉NO₄

[ Molecular Weight ]:
147.129

[ Flash Point ]:
110.0±24.6 °C

[ Exact Mass ]:
147.053162

[ PSA ]:
86.63000

[ LogP ]:
-0.44

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.494

[ Water Solubility ]:
H2O: 25 mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
22-24/25

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%