Diphenylpiperidin-4-ylmethanol hydrochloride
Names
[ CAS No. ]:
1798-50-1
[ Name ]:
Diphenylpiperidin-4-ylmethanol hydrochloride
[Synonym ]:
Azacyclono hydrochloride
Diphenylpiperidin-4-ylmethanol hydrochloride
AZACYCLONOL HYDROCHLORIDE
MFCD00039039
Diphenyl(piperidin-4-yl)methanol hydrochloride
EINECS 217-284-9
Frenquel hydrochloride
Azacyclonol HCl
alpha,alpha-Diphenyl-4-piperidinomethanol hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
445.5ºC at 760 mmHg
[ Melting Point ]:
270-281 °C
[ Molecular Formula ]:
C18H22ClNO
[ Molecular Weight ]:
303.82600
[ Flash Point ]:
142ºC
[ Exact Mass ]:
303.13900
[ PSA ]:
32.26000
[ LogP ]:
4.05290
[ Vapour Pressure ]:
1.02E-08mmHg at 25°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TN0925000
- CHEMICAL NAME :
- 4-Piperidinemethanol, alpha,alpha-diphenyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 1798-50-1
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H21-N-O.Cl-H
- MOLECULAR WEIGHT :
- 303.86
- WISWESSER LINE NOTATION :
- T6MTJ DXQR&R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 650 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 118,153,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 220 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 118,153,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 355 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 118,153,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 121 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 13(7),32,1979
Safety Information
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S24/25
[ HS Code ]:
2933399090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%