RORγt Inverse agonist 2

Names

[ CAS No. ]:
1801197-92-1

[ Name ]:
RORγt Inverse agonist 2

[Description]:

RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC50 of 119 nM[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> ROR

Research Areas >> Inflammation/Immunology

[Target]

EC50: 119 nM (RORγt)[1]

[In Vitro]

RORγt Inverse agonist 2 (Compound 26) is inactive against RORα and RORβ in either inverse agonist or agonist mode (>40 μM)[1].

[References]

[ Molecular Formula ]:
C₂₇H₂₅F₈NO₅S

[ Molecular Weight ]:
627.54