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m-PEG7-CH2-OH

Names

[ CAS No. ]:
1807512-35-1

[ Name ]:
m-PEG7-CH2-OH

[Synonym ]:
MPEG7-(CH2)3OH

Biological Activity

[Description]:

m-PEG7-CH2-OH a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. KunioOka, et al. Thermochromism and solvatochromism of non-ionic polar polysilanes. Journal of Organometallic Chemistry.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
436.2±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H34O8

[ Molecular Weight ]:
354.436

[ Flash Point ]:
217.6±27.3 °C

[ Exact Mass ]:
354.225372

[ LogP ]:
-2.52

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.450

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds