5-Hydroxy-4-methoxycanthin-6-one

Names

[ Name ]:
5-Hydroxy-4-methoxycanthin-6-one

[Synonym ]:
4-Methoxy-5-hydroxycanthin-6-one
Nigakinone
4-methoxy-5-hydroxycantin-6-one
4-Methoxy-5-hydroxy-canthin-6-on
HMS2269C08
5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
5-hydroxy-4-methoxycanthin-6-one
6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 5-hydroxy-4-methoxy-

Biological Activity

[Description]:

Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Natural Products >> Alkaloid

Research Areas >> Others

[References]

[1]. Wang N, et al. Quality Assessment of Kumu Injection, a Traditional Chinese Medicine Preparation, Using HPLC Combined with Chemometric Methods and Qualitative and Quantitative Analysis of Multiple Alkaloids by Single Marker. Molecules. 2018 Apr 9;23(4).

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
442.7±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₀N₂O₃

[ Molecular Weight ]:
266.251

[ Flash Point ]:
221.5±28.7 °C

[ Exact Mass ]:
266.069153

[ PSA ]:
63.83000

[ LogP ]:
1.92

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.747

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%