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Acetyl-ACTH (4-24) (human, bovine, rat)

Names

[ CAS No. ]:
1815618-00-8

[ Name ]:
Acetyl-ACTH (4-24) (human, bovine, rat)

[Synonym ]:
L-Proline, N-acetyl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-va lyl-L-tyrosyl-
N-Acetyl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyros yl-L-proline

Biological Activity

[Description]:

Acetyl-ACTH (4-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Others >> Androgen Receptor

[References]

[1]. K Wakamatsu , et al. Characterisation of ACTH peptides in human skin and their activation of the melanocortin-1 receptor. Pigment Cell Res. 1997 Oct;10(5):288-97.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C123H193N37O26S

[ Molecular Weight ]:
2638.15

[ Exact Mass ]:
2636.463867

[ LogP ]:
-2.52

[ Index of Refraction ]:
1.675

Related Compounds