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CDK7-IN-5

Names

[ CAS No. ]:
1817006-50-0

[ Name ]:
CDK7-IN-5

Biological Activity

[Description]:

CDK7-IN-5 is a CDK7 inhibitor with an IC50 value <100 nM. CDK7-IN-5 has anticancer effects. (WO2015154022A1 (Compound 104))[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

CDK7:<100 nM (IC50)


[In Vitro]

CDK7-IN-5 (Comp 104; 72 hours) inhibits the proliferation of A673 cells with an IC50 <500 nM[1].

[References]

[1]. Jason J. MARINEAU, et al. Inhibitors of cyclin-dependent kinase 7 (cdk7). WO2015154022A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C34H45N9O2

[ Molecular Weight ]:
611.78


Related Compounds