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β-Secretase Inhibitor I

Names

[ CAS No. ]:
1818239-19-8

[ Name ]:
β-Secretase Inhibitor I

Biological Activity

[Description]:

β-Secretase Inhibitor I is an extremely potent β-secretase inhibitor with reduced cardiovascular and liver toxicity.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Beta-secretase

Research Areas >> Neurological Disease

[References]

[1]. Tadano G, et al. Discovery of an Extremely Potent Thiazine-Based β-Secretase Inhibitor with Reduced Cardiovascular and Liver Toxicity at a Low Projected Human Dose. J Med Chem. 2019 Oct 24;62(20):9331-9337.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₈F₃N₅O₂S

[ Molecular Weight ]:
425.43

Related Compounds