NAAA-IN-3

Names

[ CAS No. ]:
1831115-59-3

[ Name ]:
NAAA-IN-3

Biological Activity

[Description]:

NAAA-IN-3 (Compound 17a) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-3 has the potential for the research of inflammation and pain[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Malamas MS, et al. Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115195.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H16N2O

[ Molecular Weight ]:
264.32

Related Compounds