BTR-1

Names

[ Name ]:
BTR-1

[Synonym ]:
3-ethyl-5-benzylidene-2-thioxo-thiazolidin-4-one
3-Aethyl-5-benzyliden-2-thioxo-thiazolidin-4-on
3-Ethyl-5-benzyliden-rhodanin
5-benzylidene-3-ethyl rhodanine

Biological Activity

[Description]:

BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[Target]

Apoptosis[1]

[References]

[1]. Moorthy BT, et al. Novel rhodanine derivatives induce growth inhibition followed by apoptosis. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6297-301.

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Boiling Point ]:
372.8ºC at 760mmHg

[ Molecular Formula ]:
C₁₂H₁₁NOS₂

[ Molecular Weight ]:
249.35200

[ Flash Point ]:
179.3ºC

[ Exact Mass ]:
249.02800

[ PSA ]:
77.70000

[ LogP ]:
2.84560

[ Vapour Pressure ]:
9.34E-06mmHg at 25°C

[ Index of Refraction ]:
1.692

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%