n-tetradecyl-beta-d-maltoside

Names

[ Name ]:
n-tetradecyl-beta-d-maltoside

[Synonym ]:
Tetradecyl 4-O-a-D-glucopyranosyl-b-D-glucopyranoside
Tetradecyl 4-O-alpha-D-Glucopyranosyl-beta-D-Glucopyranoside
tetradecylmaltoside
n-Tetradecyl |A-D-maltopyranoside
Tetradecyl-|A-D-maltoside

Biological Activity

[Description]:

Tetradecyl-β-D-maltoside is an absorption enhancer which can increase the nasal absorption of regular human insulin or the fast acting insulin analog lyspro-insulin[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Arnold JJ, et al. Reestablishment of the nasal permeability barrier to several peptides following exposure to the absorption enhancer tetradecyl-beta-D-maltoside. J Pharm Sci. 2010 Apr;99(4):1912-20.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₅₀O₁₁

[ Molecular Weight ]:
538.66900

[ Exact Mass ]:
538.33500

[ PSA ]:
178.53000

[ LogP ]:
0.32820

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: soluble10mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Synthetic long-chain alkyl maltosides and alkyl sucrose esters as enhancers of nasal insulin absorption.

J. Pharm. Sci. 91(6) , 1456-1462, (2002)

A series of new glycosides with extended alkyl side-chains (C(13-16)) linked to maltose or sucrose were synthesized and tested for their efficacy in enhancing nasal insulin absorption in anesthetized ...

Pathway of detergent-mediated and peptide ligand-mediated refolding of heterodimeric class II major histocompatibility complex (MHC) molecules.

Eur. J. Biochem. 248(3) , 684-691, (1997)

We investigated the mechanism of refolding and reassembly of recombinant alpha and beta chains of the class II major histocompatibility molecules (MHC-II) HLA-DRB5*0101. Both chains were expressed in ...

Modulation of acetylcholinesterase activity by glycoside-detergents and their solubilization efficiency for neuronal membranes from bovine nucleus caudatus.

Biochem. Biophys. Res. Commun. 106(3) , 848-855, (1982)