Antitubercular agent-26

Names

[ CAS No. ]:
1845720-46-8

[ Name ]:
Antitubercular agent-26

Biological Activity

[Description]:

Antitubercular agent-26 (Compound 32) is an orally active anti-tubercular agent with an extracellular IC50 of 0.50 μM and an intracellular IC50 of 0.51 μM against M. tuberculosis H37Rv. Antitubercular agent-26 shows good metabolic stability, low risk of cardiotoxicity and no genotoxicity[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Jin G, et al. Discovery of thienothiazolocarboxamide analogues as novel anti-tubercular agent. Bioorg Med Chem. 2020 Dec 1;28(23):115797.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H23N5O3S2

[ Molecular Weight ]:
469.58

Related Compounds