Phloxine B
Names
[ CAS No. ]:
18472-87-2
[ Name ]:
Phloxine B
[Synonym ]:
cred
red104
D and C Red No. 28
D and C red dye No 28
Disodium 2,3,4,5-tetrachloro-6-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
Food Red No. 104
MFCD00070627
RED 28
SUREDYE
Red No. 28 Eosin 10B
EOSINE B
PHLOXINE
Phloxine 92
AKA231
EINECS 242-355-6
2',4',5',7'-tetrabromo-4,5,6,7-tetrachlorofluorescein disodium salt
Benzoic acid, 2,3,4,5-tetrachloro-6-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, sodium salt (1:2)
Phloxine B disodium salt
Phloxine B,high purity,Biological stain
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Boiling Point ]:
747.3ºC at 760 mmHg
[ Molecular Formula ]:
C20H2Br4Cl4Na2O5
[ Molecular Weight ]:
829.634
[ Flash Point ]:
405.8ºC
[ Exact Mass ]:
823.518494
[ PSA ]:
81.65000
[ LogP ]:
10.20580
[ Vapour Pressure ]:
1.85E-23mmHg at 25°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LM5900000
- CHEMICAL NAME :
- Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-, disodium salt
- CAS REGISTRY NUMBER :
- 18472-87-2
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C20-H2-Br4-Cl4-O5.2Na
- MOLECULAR WEIGHT :
- 829.64
- WISWESSER LINE NOTATION :
- T C666 BO EVJ DE FE IR BG CG DG EG FVO& LE MO NE &-NA- 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75600 mg/kg/90W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors Endocrine - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 63 gm/kg
- SEX/DURATION :
- female 1-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 39600 mg/kg
- SEX/DURATION :
- female 6-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 66 gm/kg
- SEX/DURATION :
- female 6-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Human Lung
- DOSE/DURATION :
- 3 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 30,239,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4129 No. of Facilities: 301 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1460 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4129 No. of Facilities: 559 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 9866 (estimated) No. of Female Employees: 3202 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9003 No. of Facilities: 636 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 8722 (estimated) No. of Female Employees: 6754 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36
[ Safety Phrases ]:
S22-S24/25-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
LM5900000
[ HS Code ]:
32041200
Customs
[ HS Code ]: 32041200
Articles
J. Med. Microbiol. 64 , 147-56, (2015)
Candida dubliniensis is a pathogenic yeast of the genus Candida closely related to Candida albicans. The phenotypic similarity of these two species often leads to misidentification of C. dubliniensis ...
A defect of the vacuolar putative lipase Atg15 accelerates degradation of lipid droplets through lipolysis.Autophagy 11 , 1247-58, (2015)
Lipid droplets (LDs) are the conserved organelles for the deposit of neutral lipids, and function as reservoirs of membrane and energy sources. To date, functional links between autophagy and LD dynam...
On-line HPLC analysis system for metabolism and inhibition studies in precision-cut liver slices.Anal. Chem. 83(1) , 84-91, (2011)
A novel approach for on-line monitoring of drug metabolism in continuously perifused, precision-cut liver slices (PCLS) in a microfluidic system has been developed using high-performance liquid chroma...