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Propargyl-PEG2-acid

Names

[ CAS No. ]:
1859379-85-3

[ Name ]:
Propargyl-PEG2-acid

Biological Activity

[Description]:

Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C8H12O4

[ Molecular Weight ]:
172.18

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds