Bromodomain inhibitor-10

Names

[ CAS No. ]:
1870849-58-3

[ Name ]:
Bromodomain inhibitor-10

Biological Activity

[Description]:

Bromodomain inhibitor-10 (compound 128) is a potent bromodomain inhibitor with Kds of 15.0, 2500 nM for BRD4-1 and BRD4-2, respectively. Bromodomain inhibitor-10 inhibits the production of IL12p40[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[Target]

BRD4-1:15 nM (Kd)

BRD4-2:2500 nM (Kd)


[References]

[1]. Jimmi GERNER SEITZBERG, et al. Compounds active towards bromodomains. WO2016016316A1

Chemical & Physical Properties

[ Molecular Formula ]:
C20H20N4O3

[ Molecular Weight ]:
364.40

Related Compounds