FMoc-Phe(4-Boc2-guanidino)-OH

Names

[ Name ]:
FMoc-Phe(4-Boc2-guanidino)-OH

[Synonym ]:
Fmoc-4-(N,N'-di-Boc-guanidino)-L-phenylalanine
Fmoc-4-guanidino-phenylalanine(N,N'-di-Boc)-OH
FMoc-Phe(4-Boc2-guanidino)-OH
Fmoc-p-(N,N'-Boc-guanidino)Phe
MFCD02092975
FMOC-PHE(4-GUANIDINO-BOC2)-OH
4-[[Bis[[(1,1-Dimethylethoxy)Carbonyl]Amino]Methylene]Amino]-N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Phenylalanine

Biological Activity

[Description]:

Fmoc-Phe(bis-Boc-4-guanidino)-OH is a phenylalanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-957.

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Molecular Formula ]:
C₃₅H₄₀N₄O₈

[ Molecular Weight ]:
644.71400

[ Exact Mass ]:
644.28500

[ PSA ]:
164.65000

[ LogP ]:
7.43060

[ Index of Refraction ]:
1.597

[ Storage condition ]:
2-8°C

MSDS

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Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Articles

Human tissue kallikrein S1 subsite recognition of non-natural basic amino acids.

Biochemistry 40 , 5226, (2001)

We explored the unique substrate specificity of the primary S(1) subsite of human urinary kallikrein (hK1), which accepts both Phe and Arg, using internally quenched fluorescent peptides Abz-F-X-S-R-Q...