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Sieboldin

Names

[ CAS No. ]:
18777-73-6

[ Name ]:
Sieboldin

[Synonym ]:
sieboldin
3-Hydroxyphloretin-4'-β-D-glucosid
3-Hydroxy-phloretin-4'-β-D-glucosid
3-hydroxyphloretin 4'-β-D-glucoside
3-(3,4-Dihydroxy-phenyl)-1-[2,6-dihydroxy-4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-propan-1-one

Biological Activity

[Description]:

Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

Others


[References]

[1]. Kim J H, et al. Trapping of Methylglyoxal by Sieboldin from Malus baccata L. and Identification of Sieboldin-Methylglyoxal Adducts Forms[J]. Natural Product Sciences, 2021, 27(4): 245-250.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H24O11

[ Molecular Weight ]:
452.41

[ Exact Mass ]:
452.13200

[ PSA ]:
197.37000

Related Compounds