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Boc-Val-Ala-PAB

Names

[ CAS No. ]:
1884577-99-4

[ Name ]:
Boc-Val-Ala-PAB

[Synonym ]:
MFCD28557280

Biological Activity

[Description]:

Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs)[1][2].

[Related Catalog]:

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

Research Areas >> Others

[References]

[1]. HP Wilson, et al. Pyrrolobenzodiazepines and conjugates thereof: World Intellectual Property Organization, WO2016037644. 2016-03-17.

[2]. HP Wilson, et al. Preparation of pyrrolobenzodiazepine dimers and their conjugates with cell binding agents, especially pyrrolobenzodiazepine dimer drug linker antibody conjugates and their use for treating proliferative diseases, particularly cancer: World Intellectual Property Organization, WO2016038383. 2016-03-17

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₃₁N₃O₅

[ Molecular Weight ]:
393.48

Related Compounds