L-Aspartic acid, N-(4-(((2,4-diamino-5-chloro-6-quinazolinyl)methyl)amino)benzoyl)- (9CI)
Names
[ CAS No. ]:
18921-73-8
[ Name ]:
L-Aspartic acid, N-(4-(((2,4-diamino-5-chloro-6-quinazolinyl)methyl)amino)benzoyl)- (9CI)
[Synonym ]:
L-Aspartic acid,4-diamino-5-chloro-6-quinazolinyl)methyl]amino]benzoyl]
N-{4-[(2,4-diamino-5-chloro-quinazolin-6-ylmethyl)-amino]-benzoyl}-aspartic acid
Aspartic acid,4-diamino-5-chloro-6-quinazolinyl)methyl]amino]benzoyl]-,L
2-[4-(((2,4-Diamino-5-chloro-quinazolin-6-yl)methyl)amino)
Chemical & Physical Properties
[ Density]:
1.603g/cm3
[ Molecular Formula ]:
C20H19ClN6O5
[ Molecular Weight ]:
458.85500
[ Exact Mass ]:
458.11100
[ PSA ]:
193.55000
[ LogP ]:
3.34370
[ Index of Refraction ]:
1.765
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CI9310000
- CHEMICAL NAME :
- Aspartic acid, N-(p-(((2,4-diamino-5-chloro-6-quinazolinyl)methyl)am ino)benzoyl)-, L-
- CAS REGISTRY NUMBER :
- 18921-73-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H19-Cl-N6-O5
- MOLECULAR WEIGHT :
- 458.90
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 482 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 36 nmol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1947,1976